A novel approach in fabricating anionic inter-polymeric complex polysaccharide bio-platform with enhanced mechanical, structural and chemical properties for burn wound dressings. This approach implies a facile, insitu method to design soft nano-floral inter-polymeric complexes. In particular, sodium alginate (SA) and kappa-carrageenan (k-Ca) treated silver salt results in nano-floral inter-polymeric complex with self-stability. SEM images depict nano-floral complexes with surface plasmon resonance at 412-425 nm. These were resistant towards Staphylococcus aureus and Escherichia coli bacterium. These nano-floral complexes were then subjected to wound closure diameter and histological analysis. Designed polymeric complexes enhanced exudate absorption thus promotes effective proliferation, the appearance of compact fibrous arrangement and hair follicles i.e. facilitates healing for second-degree burn wound.
Keywords: Anionic polysaccharides; Polymeric burn dressing; Silver nanoparticles.
Copyright © 2020 Elsevier B.V. All rights reserved.