Draft Genome Sequences of Bifidobacterium animalis Consecutively Isolated from Healthy Japanese Individuals

Tomoya Tsukimi; Tsubasa Watabe; Kazuki Tanaka; Mitsuhiko P Sato; Haruo Suzuki; Masaru Tomita; Shinji Fukuda

doi:10.7150/jgen.38516

Draft Genome Sequences of Bifidobacterium animalis Consecutively Isolated from Healthy Japanese Individuals

J Genomics. 2020 Apr 6:8:37-42. doi: 10.7150/jgen.38516. eCollection 2020.

Authors

Tomoya Tsukimi^{1

2}, Tsubasa Watabe^{1

2}, Kazuki Tanaka^{1

2}, Mitsuhiko P Sato³, Haruo Suzuki^{1

4}, Masaru Tomita^{1

2

4}, Shinji Fukuda^{1

2

5

6

7}

Affiliations

¹ Institute for Advanced Biosciences, Keio University, 246-2 Mizukami, Kakuganji, Tsuruoka, Yamagata 997-0052, Japan.
² Systems Biology Program, Graduate School of Media and Governance, Keio University, 5322 Endo, Fujisawa, Kanagawa 252-0882, Japan.
³ Department of Bacteriology, Faculty of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi, Fukuoka 812-8582, Japan.
⁴ Faculty of Environment and Information Studies, Keio University, 5322 Endo, Fujisawa, Kanagawa 252-0882, Japan.
⁵ Intestinal Microbiota Project, Kanagawa Institute of Industrial Science and Technology, 3-25-13 Tonomachi, Kawasaki, Kanagawa 210-0821, Japan.
⁶ Transborder Medical Research Center, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan.
⁷ Metabologenomics, Inc., 246-2 Mizukami, Kakuganji, Tsuruoka, Yamagata 997-0052, Japan.

Abstract

Bifidobacterium species are well recognized as probiotics and colonized in various parts of the human body. Here, we report the draft genome sequences of Bifidobacterium animalis isolated from two healthy Japanese volunteers, one of which was sampled twice before and after a 10-year interval. A core genome phylogeny analysis indicated that the strains isolated from the same volunteer were closely related. This paper is the first report of multiple draft genome sequences of B. animalis independently isolated from the same individual and provides insight into the probiotic potential of a member of this species.

Keywords: Bifidobacterium animalis; Intestinal Microbiota; Whole-Genome Sequencing.