Simultaneous skin biome and keratinocyte genomic capture reveals microbiome differences by depth of sampling

J Allergy Clin Immunol. 2020 Dec;146(6):1442-1445. doi: 10.1016/j.jaci.2020.04.004. Epub 2020 Apr 19.

Abstract

Novel skin tape strip method allows for simultaneous collection of the skin microbiome and underlying host DNA and RNA, and reveals that microbial ecology is dependent on the depth of sampling.

Publication types

  • Clinical Trial
  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Child
  • Dermatitis, Atopic* / immunology
  • Dermatitis, Atopic* / microbiology
  • Dermatitis, Atopic* / pathology
  • Female
  • Gene Expression Regulation / immunology*
  • Humans
  • Keratinocytes* / immunology
  • Keratinocytes* / microbiology
  • Keratinocytes* / pathology
  • Male
  • Microbiota / immunology*
  • Skin* / immunology
  • Skin* / microbiology
  • Skin* / pathology