Objective: To analyze the survival and prognosis of patients with nasal extranodal natural killer/T-cell lymphoma （ENKL）.
Methods: The clinical data of newly diagnosed 52 patients with nasal NK/T-cell lymphoma from June 2012 to June 2018 were selected. Univariate and multivariate analysis was performed on the relationship between different clinical factors and prognosis by Kaplan-Meier method and COX proportional hazard model.
Results: The median overall survival (OS) time of patients was 72 months. Univariate analysis showed that age, sex, IPI score, ECOG score, hemoglobin(Hb) level, clinical stage, and treatment pattern all associated with OS of nasal NK/T-cell lymphoma patients. Multivariate analysis showed that hemoglobin level, age and clinical stage were independent factors affecting OS of nasal NK/T lymphoma patients.
Conclusion: Hemoglobin level, age and clinical stage can be used as indicators to evaluate the prognosis of nasal NK/T-cell lymphoma.
题目: 鼻腔NK/T细胞淋巴瘤患者的生存及预后分析.
目的: 分析鼻腔结外NK/T细胞淋巴瘤( extranodal natural killer/T-cell lymphoma，ENKL)患者的生存及预后状况.
方法: 选取2012年6月-2018年6月本院初治鼻腔ENKL患者52例。分别采用Kaplan-Meier法、COX比例风险模型对各个因素和预后的关系作单因素及多因素分析.
结果: 患者中位OS时间为72个月。单因素分析表明, 性别、年龄、IPI、ECOG、Hb、临床分期及治疗模式均与鼻腔ENKL患者的OS相关。多因素分析显示, Hb、年龄及临床分期是影响鼻腔ENKL患者OS的独立因素.
结论: Hb、年龄及临床分期可用于预测鼻腔ENKL患者的预后.