1 Evolution and Cancer Laboratory, Barts Cancer Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Sq, London, EC1M 6BQ, UK. daniel.temko.13@ucl.ac.uk.
2 Department of Computer Science, University College London, London, WC1E 6BT, UK. daniel.temko.13@ucl.ac.uk.
3 Centre for Mathematics and Physics in the Life Sciences and Experimental Biology (CoMPLEX), University College London, Gower Street, London, WC1E 6BT, UK. daniel.temko.13@ucl.ac.uk.
4 Institute of Cancer and Genomic Sciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
5 Department of Computer Science, University College London, London, WC1E 6BT, UK.
6 Institute of Natural Sciences, Shanghai Jiao Tong University, Dong Chuan Road, Minhang District, Shanghai, 200240, UK.
7 Ludwig Institute for Cancer Research, University of Oxford, Old Road Campus Research Building, Roosevelt Dr, Oxford, OX3 7DQ, USA. benjamin.schuster-boeckler@ludwig.ox.ac.uk.
8 Evolution and Cancer Laboratory, Barts Cancer Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Sq, London, EC1M 6BQ, UK. t.graham@qmul.ac.uk.