Podocytes: The Role of Lysosomes in the Development of Nephrotic Syndrome

Am J Pathol. 2020 Jun;190(6):1172-1174. doi: 10.1016/j.ajpath.2020.04.001. Epub 2020 Apr 16.

Authors

Marica Giliberti¹, Adele Mitrotti¹, Loreto Gesualdo²

Affiliations

¹ Nephrology Unit, Department of Emergency and Transplant Organs, University Aldo Moro of Bari, Bari, Italy.
² Nephrology Unit, Department of Emergency and Transplant Organs, University Aldo Moro of Bari, Bari, Italy. Electronic address: loreto.gesualdo@uniba.it.

PMID: 32305354
DOI: 10.1016/j.ajpath.2020.04.001

Abstract

This commentary highlights the article by Li et al that links ceramide accumulation in podocytes to cellular damage and nephrotic syndrome.

Copyright © 2020 American Society for Investigative Pathology. Published by Elsevier Inc. All rights reserved.

Publication types

Comment

MeSH terms

Animals
Ceramides
Kidney Glomerulus
Lysosomes
Mice
Nephrotic Syndrome*
Podocytes*

Substances

Ceramides