Immune escape by loss of heterozygosis of HLA genes facilitated the transmission of diffuse large B cell lymphoma from mother to offspring

Br J Haematol. 2020 Jun;189(6):e234-e237. doi: 10.1111/bjh.16662. Epub 2020 Apr 17.
No abstract available

Keywords: HLA genes; diffuse large B-cell lymphoma; loss of heterozygosis; maternal-to-fetus; transmission.

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Allografts
  • Cord Blood Stem Cell Transplantation*
  • Female
  • HLA Antigens / genetics*
  • Humans
  • Infant, Newborn
  • Loss of Heterozygosity*
  • Lymphoma, Large B-Cell, Diffuse* / genetics
  • Lymphoma, Large B-Cell, Diffuse* / metabolism
  • Lymphoma, Large B-Cell, Diffuse* / pathology
  • Lymphoma, Large B-Cell, Diffuse* / therapy
  • Maternal-Fetal Exchange*
  • Pregnancy
  • Pregnancy Complications, Neoplastic / genetics
  • Pregnancy Complications, Neoplastic / metabolism
  • Pregnancy Complications, Neoplastic / pathology
  • Pregnancy Complications, Neoplastic / therapy

Substances

  • HLA Antigens