The Imperfect Cytokine Storm: Severe COVID-19 With ARDS in a Patient on Durable LVAD Support

Vinh Q Chau; Estefania Oliveros; Kiran Mahmood; Aditi Singhvi; Anuradha Lala; Noah Moss; Umesh Gidwani; Donna M Mancini; Sean P Pinney; Aditya Parikh

doi:10.1016/j.jaccas.2020.04.001

The Imperfect Cytokine Storm: Severe COVID-19 With ARDS in a Patient on Durable LVAD Support

JACC Case Rep. 2020 Jul 15;2(9):1315-1320. doi: 10.1016/j.jaccas.2020.04.001. Epub 2020 Apr 8.

Authors

Affiliation

¹ Division of Cardiology, Department of Medicine, Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, New York.

Abstract

As health systems worldwide grapple with the coronavirus disease-2019 (COVID-19) pandemic, patients with durable LVAD support represent a unique population at risk for the disease. This paper outlines the case of such a patient who developed COVID-19 complicated by a "cytokine storm" with severe acute respiratory distress syndrome and myocardial injury and describes the challenges that arose during management.

Keywords: ARDS; ARDS, acute respiratory distress syndrome; COVID-19; COVID-19, coronavirus disease-2019; LVAD; LVAD, left ventricular assist device; MODS, multiorgan dysfunction syndrome; PEA, pulseless electrical activity; RV, right ventricle; SARS-CoV-2, severe acute respiratory syndrome-coronavirus-2; cytokine storm.

Publication types

Case Reports