Eruptive melanocytic nevi during etanercept treatment in an ankylosing spondylitis patient: Case report

Dermatol Ther. 2020 May;33(3):e13407. doi: 10.1111/dth.13407. Epub 2020 May 3.

Abstract

Eruptive melanocytic nevi (EMN) are rare multiple melanocytic lesions that rare and associated with dermatological and systemic diseases. Drug induced EMN is also reported with the use of biological or nonbiological chemotherapeutics, immunosuppressive agents, and melanocyte stimulators. In recent years, the increasing use of biological drugs resulted in an increased reports of EMN induced by these drugs. The objective of this abstract is reporting EMN in a patient receiving etanercept treatment. In addition, we also present a literature review of the previously cases with anti-tumor necrosis factor-α biological agents.

Keywords: anti-TNF-α agent; eruptive nevi; etanercept.

Publication types

  • Case Reports

MeSH terms

  • Etanercept / adverse effects
  • Humans
  • Immunosuppressive Agents / adverse effects
  • Nevus, Pigmented* / chemically induced
  • Nevus, Pigmented* / diagnosis
  • Skin Neoplasms* / chemically induced
  • Skin Neoplasms* / drug therapy
  • Spondylitis, Ankylosing* / diagnosis
  • Spondylitis, Ankylosing* / drug therapy
  • Tumor Necrosis Factor-alpha

Substances

  • Immunosuppressive Agents
  • Tumor Necrosis Factor-alpha
  • Etanercept