Wernicke Encephalopathy and Lactic Acidosis in Thiamine Deficiency

Indian Pediatr. 2020 Apr 15;57(4):369-370.

Abstract

Thiamine deficiency can cause encephalopathy (Wernicke) and lactic acidosis. Herein we report a 6-year-old girl on total parenteral nutrition (TPN) who developed lactic acidosis and neurological symptoms due to improper vitamin replacement, which responded to thiamine injection. The MRI brain findings were not typical for Wernicke encephalopathy.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Acidosis, Lactic* / etiology
  • Child
  • Female
  • Humans
  • Parenteral Nutrition, Total
  • Thiamine / therapeutic use
  • Thiamine Deficiency* / complications
  • Thiamine Deficiency* / drug therapy
  • Wernicke Encephalopathy* / diagnosis
  • Wernicke Encephalopathy* / drug therapy
  • Wernicke Encephalopathy* / etiology

Substances

  • Thiamine