Green Approaches to Sample Preparation Based on Extraction Techniques

Molecules. 2020 Apr 9;25(7):1719. doi: 10.3390/molecules25071719.

Abstract

Preparing a sample for analysis is a crucial step of many analytical procedures. The goal of sample preparation is to provide a representative, homogenous sample that is free of interferences and compatible with the intended analytical method. Green approaches to sample preparation require that the consumption of hazardous organic solvents and energy be minimized or even eliminated in the analytical process. While no sample preparation is clearly the most environmentally friendly approach, complete elimination of this step is not always practical. In such cases, the extraction techniques which use low amounts of solvents or no solvents are considered ideal alternatives. This paper presents an overview of green extraction procedures and sample preparation methodologies, briefly introduces their theoretical principles, and describes the recent developments in food, pharmaceutical, environmental and bioanalytical chemistry applications.

Keywords: ecofriendly extraction techniques; environmentally friendly analytical processes; green analytical chemistry.

Publication types

  • Review

MeSH terms

  • Chemical Fractionation* / methods
  • Green Chemistry Technology*
  • Liquid-Liquid Extraction
  • Solid Phase Extraction
  • Solid Phase Microextraction
  • Solvents
  • Specimen Handling

Substances

  • Solvents