Giant placental chorioangioma followed by circulatory failure of the newborn and infantile hemangioma: Case report

J Neonatal Perinatal Med. 2020;13(1):135-138. doi: 10.3233/NPM-180118.

Abstract

Placental chorioangioma (CA) is a benign placental tumor. No specific treatment is required for asymptomatic cases. We report a female infant born to a mother with giant placental CA. However fetal growth was normal and, fetal hydrops was not detected by ultrasound examination until delivery, she had hydrops, subgaleal hematoma, thrombocytopenia, hemolytic anemia, respiratory distress and circulatory failure after birth. She was successfully treated without any neurological sequelae. At 2 months of age, infantile hemangioma appeared in her lower lip. The present case suggested that giant placental CA might cause postnatal problems and be associated with the development of infantile hemangioma.

Keywords: Placental chorioangioma; fetal hydrops; hydrops; infantile hemangioma; placental tumor.

Publication types

  • Case Reports

MeSH terms

  • Adrenergic beta-Antagonists / therapeutic use
  • Anemia, Hemolytic / etiology*
  • Anemia, Hemolytic / therapy
  • Disseminated Intravascular Coagulation / etiology
  • Disseminated Intravascular Coagulation / therapy
  • Edema / etiology*
  • Edema / therapy
  • Erythrocyte Transfusion
  • Female
  • Hemangioma / complications*
  • Hemangioma / diagnostic imaging
  • Hemangioma / drug therapy
  • Hemangioma / pathology
  • Hepatomegaly / etiology
  • Humans
  • Hypoalbuminemia / etiology
  • Hypoalbuminemia / therapy
  • Infant, Newborn
  • Lip Neoplasms / drug therapy
  • Lip Neoplasms / pathology*
  • Placenta Diseases / diagnostic imaging
  • Placenta Diseases / pathology*
  • Plasma
  • Pregnancy
  • Pregnancy Complications, Neoplastic / diagnostic imaging
  • Pregnancy Complications, Neoplastic / pathology*
  • Propranolol / therapeutic use
  • Purpura / etiology
  • Purpura / therapy
  • Respiratory Distress Syndrome, Newborn / etiology*
  • Respiratory Distress Syndrome, Newborn / therapy
  • Shock / etiology*
  • Shock / therapy
  • Splenomegaly / etiology
  • Thrombocytopenia / etiology
  • Thrombocytopenia / therapy
  • Tumor Burden
  • Ultrasonography, Prenatal
  • Vasoconstrictor Agents / therapeutic use

Substances

  • Adrenergic beta-Antagonists
  • Vasoconstrictor Agents
  • Propranolol