Comparing the Japanese Version of the Ocular Surface Disease Index and Dry Eye-Related Quality-of-Life Score for Dry Eye Symptom Assessment

Takenori Inomata; Masahiro Nakamura; Masao Iwagami; Akie Midorikawa-Inomata; Yuichi Okumura; Keiichi Fujimoto; Nanami Iwata; Atsuko Eguchi; Hurramhon Shokirova; Maria Miura; Kenta Fujio; Ken Nagino; Shuko Nojiri; Akira Murakami

doi:10.3390/diagnostics10040203

Comparing the Japanese Version of the Ocular Surface Disease Index and Dry Eye-Related Quality-of-Life Score for Dry Eye Symptom Assessment

Diagnostics (Basel). 2020 Apr 7;10(4):203. doi: 10.3390/diagnostics10040203.

Authors

Takenori Inomata^{1

2

3}, Masahiro Nakamura⁴, Masao Iwagami⁵, Akie Midorikawa-Inomata³, Yuichi Okumura⁶, Keiichi Fujimoto⁶, Nanami Iwata⁶, Atsuko Eguchi³, Hurramhon Shokirova⁶, Maria Miura⁶, Kenta Fujio⁶, Ken Nagino³, Shuko Nojiri⁷, Akira Murakami^{1

6}

Affiliations

¹ Department of Ophthalmology, Juntendo University Faculty of Medicine, Tokyo 1130033, Japan.
² Department of Strategic Operating Room Management and Improvement, Juntendo University Faculty of Medicine, Tokyo 1130033, Japan.
³ Department of Hospital Administration, Juntendo University Graduate School of Medicine, Tokyo 1130033, Japan.
⁴ Precision Health, Department of Bioengineering, Graduate School of Engineering, The University of Tokyo, Tokyo 1138656, Japan.
⁵ Department of Health Services Research, University of Tsukuba, Ibaraki 3050006, Japan.
⁶ Department of Ophthalmology, Juntendo University Graduate School of Medicine, Tokyo 1130033, Japan.
⁷ Department of Medical Technology Center, Juntendo University Faculty of Medicine, Tokyo 1130033, Japan.

Abstract

The aim of this study was to compare patient-reported symptoms of dry eye disease (DED) between the Japanese version of the Ocular Surface Disease Index (J-OSDI) and the Dry Eye-Related Quality-of-Life Score (DEQS). A total of 169 participants were enrolled between September 2017 and May 2018. Patients were administered the J-OSDI and DEQS questionnaires at their first (baseline) and follow-up visits to evaluate DED-related symptoms. The correlations between the J-OSDI total score and DEQS (Frequency and Degree) scores were evaluated using Pearson's correlation coefficient, and their clinical differences were assessed using the Bland-Altman analysis. At the baseline visit, the J-OSDI score and DEQS (Frequency and Degree) were significantly correlated (r = 0.855, r = 0.897, respectively). Moreover, a significant correlation was found between the J-OSDI score and DEQS (Frequency and Degree) at the follow-up visit (r = 0.852, r = 0.888, respectively). The Bland-Altman analysis revealed a difference (bias) of 4.18 units at the baseline and 4.08 units at the follow-up between the scores of the two questionnaires. The J-OSDI and DEQS were significantly correlated with negligible score differences, suggesting that the J-OSDI can be reliably used for Japanese patients, allowing for cross-country comparisons.

Keywords: J-OSDI; dry eye disease; dry eye-related quality-of-life score; japanese version of OSDI; ocular surface disease index; questionnaire; subjective symptom.