Engineering Life: A Review of Synthetic Biology

Artif Life. 2020 Spring;26(2):260-273. doi: 10.1162/artl_a_00318. Epub 2020 Apr 9.

Abstract

Synthetic biology is a field of scientific research that applies engineering principles to living organisms and living systems. It is a field that is increasing in scope with respect to organisms engineered, practical outcomes, and systems integration. There is a commercial dimension as well, where living organisms are engineered as green technologies that could offer alternatives to industrial standards in the pharmaceutical and petroleum-based chemical industries. This review attempts to provide an introduction to this field as well as a consideration of important contributions that exemplify how synthetic biology may be commensurate or even disproportionate with the complexity of living systems. The engineerability of living systems remains a difficult task, yet advancements are reported at an ever-increasing pace.

Keywords: Synthetic biology; artificial cell; genetic engineering; metabolic engineering.

Publication types

  • Review

MeSH terms

  • Life*
  • Synthetic Biology / methods*