The Many Difficulties and Subtleties in the Cognitive Assessment of Chronic Hepatitis C Infection

Jefferson Abrantes; Daniel Simplicio Torres; Carlos Eduardo Brandão-Mello

doi:10.1155/2020/9675235

The Many Difficulties and Subtleties in the Cognitive Assessment of Chronic Hepatitis C Infection

Int J Hepatol. 2020 Mar 19:2020:9675235. doi: 10.1155/2020/9675235. eCollection 2020.

Authors

Jefferson Abrantes¹, Daniel Simplicio Torres¹, Carlos Eduardo Brandão-Mello²

Affiliations

¹ Department of Neurology, Federal University of the State of Rio de Janeiro, Rua Mariz e Barros, 775 - Tijuca, Rio de Janeiro 20270-004, Brazil.
² Department of Gastroenterology, Federal University of the State of Rio de Janeiro, Brazil.

Abstract

Since the discovery of HCV in 1989, several diseases have been related to chronic infection by this virus. Often, patients with hepatitis C virus (HCV) complain of cognitive impairment even before the development of hepatic cirrhosis, which they described as "brain fog." Several studies have proposed a link between chronic HCV infection and the development of cognitive alterations, but the inclusion of confounding factors in their samples significantly limits the analysis of the results. In this article, we will give an overview about cognitive dysfunction in patients with HCV.

Publication types

Review