One-pot sonochemical synthesis of CuS nanoplates decorated partially reduced graphene oxide for biosensing of dopamine neurotransmitter

Selvakumar Palanisamy; Sethupathi Velmurugan; Thomas C K Yang

doi:10.1016/j.ultsonch.2020.105043

One-pot sonochemical synthesis of CuS nanoplates decorated partially reduced graphene oxide for biosensing of dopamine neurotransmitter

Ultrason Sonochem. 2020 Jun:64:105043. doi: 10.1016/j.ultsonch.2020.105043. Epub 2020 Feb 22.

Authors

Selvakumar Palanisamy¹, Sethupathi Velmurugan², Thomas C K Yang³

Affiliations

¹ Center of Precision Analysis and Material Research, National Taipei University of Technology, No. 1, Section 3, Chung-Hsiao East Road, Taipei 106, Taiwan, ROC. Electronic address: prmselva@gmail.com.
² Department of Chemical Engineering and Biotechnology, National Taipei University of Technology, No. 1, Section 3, Chung-Hsiao East Road, Taipei 106, Taiwan, ROC.
³ Center of Precision Analysis and Material Research, National Taipei University of Technology, No. 1, Section 3, Chung-Hsiao East Road, Taipei 106, Taiwan, ROC; Department of Chemical Engineering and Biotechnology, National Taipei University of Technology, No. 1, Section 3, Chung-Hsiao East Road, Taipei 106, Taiwan, ROC. Electronic address: ckyang@mail.ntut.edu.tw.

PMID: 32248041
DOI: 10.1016/j.ultsonch.2020.105043

Abstract

The sonochemical methods have been used as a straight forward method for the synthesis of various composite materials, including the transition metal dichalcogenide composites. In the present work, we report a simple sonochemical synthesis of CuS nanoplates decorated partially reduced graphene oxide (PrGO) nanocomposite for the first time. The PrGO-CuS nanocomposite was synthesized using bath-sonication (frequency: 37 kHz; power: 150 W) of graphene oxide (GO), and CuS precursors at 80 °C for 60 min. The physicochemical characterization (FESEM, XRD, FTIR, and Raman spectroscopy) results confirmed the successful formation of CuS nanoplates on PrGO nanosheets. The as-synthesized PrGO-CuS nanocomposite was further utilized for electroanalysis of dopamine neurotransmitter. The obtained electroanalytical results revealed that PrGO-CuS nanocomposite has superior electrochemical activity towards dopamine than those obtained for GO, CuS, and GO-CuS composite. The fabricated biosensor shows a lower limit of detection (0.022 µM) with a more comprehensive linear response range (0.1-155.1 µM) for the detection of dopamine. Moreover, the PrGO-CuS nanocomposite electrode was successfully used for the detection of dopamine in bovine serum albumin.

Keywords: Biosensor; CuS nanoplates; Neurotransmitter; Partially reduced graphene oxide; Sonochemical synthesis.

MeSH terms

Biosensing Techniques*
Chemistry Techniques, Synthetic
Copper / chemistry*
Dopamine / analysis*
Graphite / chemistry*
Models, Molecular
Molecular Conformation
Neurotransmitter Agents / analysis*
Oxidation-Reduction
Ultrasonic Waves*

Substances

Neurotransmitter Agents
graphene oxide
Graphite
Copper
cupric sulfide
Dopamine