Social Impact of Hepatic Encephalopathy

Clin Liver Dis. 2020 May;24(2):291-301. doi: 10.1016/j.cld.2020.01.008. Epub 2020 Mar 2.

Abstract

Hepatic encephalopathy (HE) is a multifaceted disorder, with effects stretching far beyond office visits and hospitalizations. Patients with HE suffer from varying degrees of altered consciousness, intellectual disability, and personality changes. A large social impact exists for patients with HE. Quality of life and activities of daily living, such as work capacity, driving ability, and sleep quality, have been shown to be affected. Additionally, caregiver and financial burdens are highly prevalent. Multiple tools exist to assess quality of life, including the CLD-Q questionnaire. Common treatments for HE, including rifaximin and lactulose, have been shown to improve overall quality of life.

Keywords: Caregiver; Driving; Finance; Quality of life; Sleep; Social impact.

Publication types

  • Review

MeSH terms

  • Activities of Daily Living
  • Automobile Driving*
  • Caregivers / economics
  • Caregivers / psychology
  • Employment*
  • Gastrointestinal Agents / therapeutic use
  • Hepatic Encephalopathy* / complications
  • Hepatic Encephalopathy* / drug therapy
  • Humans
  • Lactulose / therapeutic use
  • Quality of Life*
  • Rifaximin / therapeutic use
  • Sleep Wake Disorders / etiology

Substances

  • Gastrointestinal Agents
  • Lactulose
  • Rifaximin