Abstract
Skin manifestations of systemic disease and malignancy are extremely polymorphous. Clinicians should be familiarized with paraneoplastic dermatoses in order to perform an early diagnosis of the underlying neoplasm. Lack of familiarity with cutaneous clues of internal malignancy may delay diagnosis and treatment of cancer. In this review, we described several paraneoplastic dermatoses and discussed extensively two paradigmatic ones, namely paraneoplastic pemphigus and paraneoplastic dermatomyositis.
Keywords:
diagnosis; neoplasia; paraneoplastic dermatomyositis; paraneoplastic dermatoses; paraneoplastic pemphigus; skin features.
MeSH terms
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Cytokines / metabolism
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Dermatomyositis / metabolism
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Dermatomyositis / pathology
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Dermatomyositis / physiopathology*
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Erythema / metabolism
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Erythema / pathology
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Erythema / physiopathology
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Humans
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Neoplasms / diagnosis*
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Neoplasms / metabolism
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Neoplasms / physiopathology
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Paraneoplastic Syndromes / diagnosis*
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Paraneoplastic Syndromes / metabolism
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Paraneoplastic Syndromes / physiopathology
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Pemphigus / metabolism
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Pemphigus / pathology
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Pemphigus / physiopathology*
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Pyoderma Gangrenosum / metabolism
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Pyoderma Gangrenosum / pathology
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Pyoderma Gangrenosum / physiopathology
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Skin / metabolism
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Skin / pathology*
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Skin Diseases / metabolism
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Skin Diseases / pathology
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Skin Diseases / physiopathology
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Sweet Syndrome / metabolism
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Sweet Syndrome / pathology
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Sweet Syndrome / physiopathology