Balneotherapy with Chinese herbal medicine prolongs the remission period in patients with psoriasis vulgaris

Dermatol Ther. 2020 May;33(3):e13351. doi: 10.1111/dth.13351. Epub 2020 Apr 24.

Abstract

This study aimed to evaluate whether the supplementary balneotherapy with Chinese herbal medicine (CHM) could facilitate the treatment of psoriasis vulgaris and thus be beneficial for long-term remission from the symptoms. Two hundred psoriasis vulgaris patients with moderate-to-severe plaque psoriasis from January 2013 to June 2014 were evenly divided into two groups: the consolidated therapy group (CTG) and unconsolidated therapy group (UTG); the remission period of the two groups was compared. There was no significant difference in Psoriasis Area Severity Index (PASI) score between the two groups at the beginning and the end of the treatment. However, the average remission time in CTG was 10.99 months, which was significantly longer than that of 7.94 months in UTG (P = .001). After a correction of age, course of disease, skin type as well as PASI baseline value using a COX model, we found that the risk of recurrence of psoriasis vulgaris in UTG was higher than that in the CTG (P < .001). No adverse reactions were discovered when combing the two treatments together. The combined treatment of CHM balneotherapy and narrowband ultraviolet B could significantly prolong the remission time in patients with psoriasis vulgaris.

Keywords: CHM balneotherapy; NB-UVB; psoriasis area severity index; psoriasis vulgaris; remission period.

MeSH terms

  • Balneology*
  • Combined Modality Therapy
  • Drugs, Chinese Herbal*
  • Humans
  • Psoriasis* / diagnosis
  • Psoriasis* / drug therapy
  • Treatment Outcome
  • Ultraviolet Therapy*

Substances

  • Drugs, Chinese Herbal