[Antioxidant treatment promotes lung cancer while protecting against lung emphysema]

Med Sci (Paris). 2020 Mar;36(3):200-203. doi: 10.1051/medsci/2020030. Epub 2020 Mar 31.

[Article in French]

Authors

Marielle Breau¹, David Bernard², Fatima Mechta-Grigoriou³, Serge Adnot¹

Affiliations

¹ Inserm U955, Département de physiologie-explorations fonctionnelles, and DHU A-TVB hôpital Henri Mondor, AP-HP, 94010 Créteil, France.
² Centre de recherche en cancérologie de Lyon, UMR Inserm U1052/CNRS 5286, Université de Lyon, Centre Léon Bérard, 69008 Lyon, France.
³ Stress and cancer laboratory, équipe labellisée LNCC, Institut Curie, Inserm, U830, 75005 Paris, France.

PMID: 32228832
DOI: 10.1051/medsci/2020030

No abstract available

Publication types

News

MeSH terms

Acetylcysteine / adverse effects
Acetylcysteine / therapeutic use
Animals
Antioxidants / adverse effects*
Antioxidants / therapeutic use*
Cell Transformation, Neoplastic / chemically induced
Cell Transformation, Neoplastic / genetics
Cell Transformation, Neoplastic / pathology
Cellular Senescence / drug effects
Cellular Senescence / genetics
Cytoprotection / drug effects
Cytoprotection / genetics
Humans
Lung / cytology
Lung / drug effects
Lung / metabolism
Lung Neoplasms / chemically induced*
Lung Neoplasms / genetics
Mice
Mice, Knockout
Oxidative Stress / drug effects
Oxidative Stress / physiology
Proto-Oncogene Proteins c-jun / genetics
Proto-Oncogene Proteins c-jun / physiology
Pulmonary Emphysema / prevention & control*

Substances

Antioxidants
JunD protein, human
Proto-Oncogene Proteins c-jun
junD protein, mouse
Acetylcysteine