Drug-Induced Cough

Physiol Res. 2020 Mar 27;69(Suppl 1):S81-S92. doi: 10.33549/physiolres.934406.

Abstract

Since the recognition of angiotensin-converting enzyme inhibitors (ACEIs)-induced cough, drug has been considered as a potential cause of chronic cough. This review presents recent knowledge on drug-induced coughs in patients with chronic cough. The focus is placed on ACEIs, for which there are a multitude of studies documenting their associations with cough. Additional drugs are discussed for which there are reports of cough as a side effect of treatment, and the potential mechanisms of these effects are discussed.

Publication types

  • Review

MeSH terms

  • Analgesics, Opioid / adverse effects
  • Angiotensin-Converting Enzyme Inhibitors / adverse effects*
  • Animals
  • Calcium Channel Blockers / adverse effects
  • Chronic Disease
  • Cough / chemically induced*
  • Cough / diagnosis
  • Cough / physiopathology*
  • Fentanyl / adverse effects
  • Humans
  • Reflex / drug effects
  • Reflex / physiology

Substances

  • Analgesics, Opioid
  • Angiotensin-Converting Enzyme Inhibitors
  • Calcium Channel Blockers
  • Fentanyl