In this work, the DC two-photon absorption signal offset (${{\rm DC}_{\rm TPA}}$DCTPA) and the amplitude of the autocorrelation (${{\rm A}_{\rm AC}}$AAC) are measured simultaneously around the focal point of an apochromatic microscope objective using the z-scan autocorrelation technique. The ${{\rm A}_{\rm AC}}$AAC is obtained from the nonlinear sensor response given by the two-photon-absorption, generated in a GaAsP photodiode, for femtosecond laser pulses. We verify that the change in the ${{\rm DC}_{\rm TPA}}$DCTPA signal along $z$z is coincident with the amplitude of the intensity autocorrelation, and that the highest amplitude of the AC is reached at the same position as the highest amplitude of the ${{\rm DC}_{\rm TPA}}$DCTPA signal. The ${{\rm DC}_{\rm TPA}}$DCTPA signal is typically used as a reference for the alignment in a collinear intensity autocorrelator, and we show that it can also be used as a practical procedure to estimate the depth of focus. The ${{\rm DC}_{\rm TPA}}$DCTPA signal measurement allows us to locate the optimum spatial-temporal coupling given by the highest amplitude of the intensity autocorrelation. Additionally, we find a variation in the pulse duration within the same region due to the radially varying group delay dispersion.