Vemurafenib-induced DRESS/DIHS resulting in spontaneous melanoma regression: an immunological reaction shedding new light on melanoma treatment?

Int J Dermatol. 2020 May;59(5):e139-e141. doi: 10.1111/ijd.14852. Epub 2020 Mar 25.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / administration & dosage
  • Antineoplastic Combined Chemotherapy Protocols / adverse effects*
  • Azetidines / administration & dosage
  • Biopsy
  • Drug Hypersensitivity Syndrome / diagnosis
  • Drug Hypersensitivity Syndrome / drug therapy
  • Drug Hypersensitivity Syndrome / immunology*
  • Female
  • Glucocorticoids / therapeutic use
  • Humans
  • Lung / diagnostic imaging
  • Lung / immunology
  • Lung Neoplasms / diagnosis
  • Lung Neoplasms / drug therapy*
  • Lung Neoplasms / immunology
  • Lung Neoplasms / secondary
  • Melanoma / diagnosis
  • Melanoma / drug therapy*
  • Melanoma / immunology
  • Melanoma / secondary
  • Middle Aged
  • Piperidines / administration & dosage
  • Positron Emission Tomography Computed Tomography
  • Skin / diagnostic imaging
  • Skin / drug effects
  • Skin / immunology
  • Skin / pathology
  • Skin Neoplasms / diagnosis
  • Skin Neoplasms / drug therapy*
  • Skin Neoplasms / immunology
  • Skin Neoplasms / pathology
  • Treatment Outcome
  • Vemurafenib / administration & dosage
  • Vemurafenib / adverse effects*

Substances

  • Azetidines
  • Glucocorticoids
  • Piperidines
  • Vemurafenib
  • cobimetinib