In-vitro antibacterial, antioxidant potentials and cytotoxic activity of the leaves of Tridax procumbens

Asad Syed; Natarajan Benit; Abdullah A Alyousef; Abdulaziz Alqasim; Mohammed Arshad

doi:10.1016/j.sjbs.2019.12.031

In-vitro antibacterial, antioxidant potentials and cytotoxic activity of the leaves of Tridax procumbens

Saudi J Biol Sci. 2020 Feb;27(2):757-761. doi: 10.1016/j.sjbs.2019.12.031. Epub 2019 Dec 26.

Authors

Asad Syed¹, Natarajan Benit², Abdullah A Alyousef³, Abdulaziz Alqasim³, Mohammed Arshad³

Affiliations

¹ Department of Botany and Microbiology, College of Science, King Saud University, P.O. Box 2455 Riyadh 11451, Saudi Arabia.
² Department of Botany, Holy Cross College, Manonmaniam Sundaranar University, Abishekapatti, Tirunelveli 627 012, Tamil Nadu, India.
³ Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Saud University, P.O. Box 10219, Riyadh 11433, Saudi Arabia.

Abstract

The present study explored the phytochemicals, antibacterial, antioxidant and cytotoxic effect of Tridax procumbens leaves. The leaves were dried and extracted with various organic solvents. The leaves contained the phytochemicals such as alkaloids, carbohydrates, polyphenols and tannins respectively. Antimicrobial potentials of the extracts were determined by performing the disc diffusion techniques. Results revealed that different organic solvents extracts namely methanol, ethanol and ethyl acetate extracts documented comparatively good activity against the studied microbial strains. The methanol extract of leaves of T. procumbens showed combatively better antioxidant potential. The tested plant leaf extract showed high activity against human lung cancer cells than breast cancer cell lines. 250 µg/ml plants extract showed 84 ± 2.8% toxicity against human lung cancer cells.

Keywords: Antibacterial; Anticancer; Antioxidant; Medicinal plants; Phytochemical; Tridax procumbens.