Stereolithography 3D Bioprinting

Methods Mol Biol. 2020:2140:93-108. doi: 10.1007/978-1-0716-0520-2_6.

Abstract

Stereolithography (SLA) 3D bioprinting has emerged as a prominent bioprinting method addressing the requirements of complex tissue fabrication. This chapter addresses the advancement in SLA 3D bioprinting in concurrent with the development of novel photocrosslinkable biomaterials with enhanced physical and chemical properties. We discuss the cytocompatible photoinitiators operating in the wide spectrum of the ultraviolet (UV) and the visible light and high-resolution dynamic mask projection systems with a suitable illumination source. The potential of SLA 3D bioprinting has been explored in various themes, like bone and neural tissue engineering and in the development of controlled microenvironments to study cell behavior. The flexible design and versatility of SLA bioprinting makes it an attractive bioprinting process with myriad possibilities and clinical applications.

Keywords: Hydrogel scaffolds; Photocrosslinking; Stereolithography 3D bioprinting; Tissue and organ regeneration.

MeSH terms

  • Biocompatible Materials
  • Bioprinting*
  • Equipment Design
  • Guided Tissue Regeneration
  • Humans
  • Hydrogels / radiation effects
  • Imaging, Three-Dimensional
  • Lighting / instrumentation
  • Lighting / methods
  • Microtechnology
  • Photochemistry
  • Polymerization / radiation effects
  • Printing, Three-Dimensional*
  • Stereolithography*
  • Tissue Engineering / methods
  • Tissue Scaffolds

Substances

  • Biocompatible Materials
  • Hydrogels