Relationship Between Serum Vitamin D Level and Ectopic Pregnancy: A Case-Control Study

J Family Reprod Health. 2019 Sep;13(3):167-172.

Abstract

Objective: To compare the difference in Vitamin D level between women with ectopic pregnancy and control group. Materials and methods: In the present case-control study, 150 patients with ectopic pregnancy were included as case group and 150 women with normal pregnancy as a control group. Then, serum vitamin D levels were measured in both groups and they were then compared with each other. P less than 0.05 was considered statistically significant. Results: The mean age in ectopic pregnancy group was 28.12 ± 5.91 and 27.35 ± 6.21 years old in control group; the difference between two groups was not statistically significant (p = 0.43). The vitamin D level in control group was higher than that of ectopic pregnancy group (p = 0.002). Of all patients, 182 patients (60.66%) had vitamin D deficiency and 64 patients (21.33%) had vitamin D insufficiency. Conclusion: Serum vitamin D level among patients with ectopic pregnancy was statistically lower than women with normal pregnancy.

Keywords: Ectopic Pregnancy; Pregnancy; Vitamin D Deficiency.