Organ Donation and Primary Central Nervous System Tumors

A Cacciatori; M Godino; M Bengochea; H Prinzo

doi:10.1016/j.transproceed.2020.02.013

Organ Donation and Primary Central Nervous System Tumors

Transplant Proc. 2020 May;52(4):1024-1029. doi: 10.1016/j.transproceed.2020.02.013. Epub 2020 Mar 19.

Authors

A Cacciatori¹, M Godino², M Bengochea², H Prinzo³

Affiliations

¹ National Institute of Donations and Transplants, Montevideo, Uruguay. Electronic address: armataba@gmail.com.
² National Institute of Donations and Transplants, Montevideo, Uruguay.
³ Department of Neurosurgery, UDELAR, Montevideo, Uruguay.

PMID: 32199648
DOI: 10.1016/j.transproceed.2020.02.013

Abstract

Primary central nervous system tumors can be the cause of brain death. Not all of them contraindicate the donation of organs and tissues for transplant. A survey of cases was carried out in our country in which it was observed that the number of brain deaths caused by primary tumors was low, of the order of 2%, with an ẋ (media) of 3 by year, which would increase the potential for donation. Medical records, an anatomopathologic study, and a detailed physical examination will be fundamental when applying the donor selection criteria. Nuclear magnetic resonance in expert hands has a sensitivity of 96% to catalog the benignity or malignancy of this type of tumors.

Publication types

Review

MeSH terms

Brain Death / diagnosis
Central Nervous System Neoplasms* / mortality
Central Nervous System Neoplasms* / pathology
Donor Selection / classification
Donor Selection / methods*
Humans
Tissue Donors* / classification
Tissue Donors* / statistics & numerical data
Tissue Donors* / supply & distribution
Tissue and Organ Procurement / methods*