Methylisothiazolinone in children's nail polish

Sara A Kullberg; Rachit Gupta; Erin M Warshaw

doi:10.1111/pde.14147

Methylisothiazolinone in children's nail polish

Pediatr Dermatol. 2020 Jul;37(4):745-747. doi: 10.1111/pde.14147. Epub 2020 Mar 20.

Authors

Sara A Kullberg^{1

2}, Rachit Gupta^{1

2}, Erin M Warshaw^{1

3}

Affiliations

¹ Park Nicollet Contact Dermatitis Clinic, Minneapolis, Minnesota.
² University of Minnesota Medical School, Minneapolis, Minnesota.
³ Department of Dermatology, University of Minnesota, Minneapolis, Minnesota.

PMID: 32198778
DOI: 10.1111/pde.14147

Abstract

Isothiazolinones, preservatives including methylisothiazolinone (MI), methylchloroisothiazolinone/methylisothiazolinone (MCI/MI), benzisothiazolinone (BIT), and octylisothiazolinone (OIT), are notorious contact allergens. Pediatric dermatologists are familiar with these preservatives in personal care products, homemade slime recipes, and wet wipes. We present a novel source of MI declared in nail polish marketed to children.

Keywords: allergy; contact dermatitis.

MeSH terms

Child
Cosmetics* / adverse effects
Dermatitis, Allergic Contact* / etiology
Humans
Patch Tests
Preservatives, Pharmaceutical / adverse effects
Thiazoles

Substances

2-methyl-4-isothiazolin-3-one
Cosmetics
Preservatives, Pharmaceutical
Thiazoles