Treatment of Staphylococcal Device Infections: Synergistic Daptomycin With Ceftaroline Versus Rifampin-Adjunct Therapy

Amy T Chang; Reese A Cosimi; Markian R Bochan

doi:10.1093/ofid/ofaa072

Treatment of Staphylococcal Device Infections: Synergistic Daptomycin With Ceftaroline Versus Rifampin-Adjunct Therapy

Open Forum Infect Dis. 2020 Feb 28;7(3):ofaa072. doi: 10.1093/ofid/ofaa072. eCollection 2020 Mar.

Authors

Amy T Chang¹, Reese A Cosimi¹, Markian R Bochan²

Affiliations

¹ Pharmacy Department, Indianapolis, Indiana, USA.
² Infectious Disease Department, Indianapolis, Indiana, USA.

Abstract

This is a single-center retrospective observational cohort study comparing daptomycin/ceftaroline combination therapy with rifampin-adjunct therapy for the treatment of staphylococcal device infections. The results of this study support use of the daptomycin/ceftaroline as an alternative or salvage option to standard of care.

Keywords: Staphylococcus; ceftaroline; daptomycin; device infections.