Proteolytic Proteoforms: Elusive Components of Hormonal Pathways?

Chen Liu; Anna Törnkvist; Spyridoula Charova; Simon Stael; Panagiotis N Moschou

doi:10.1016/j.tplants.2020.01.002

Proteolytic Proteoforms: Elusive Components of Hormonal Pathways?

Trends Plant Sci. 2020 Apr;25(4):325-328. doi: 10.1016/j.tplants.2020.01.002. Epub 2020 Feb 11.

Authors

Chen Liu¹, Anna Törnkvist¹, Spyridoula Charova², Simon Stael³, Panagiotis N Moschou⁴

Affiliations

¹ Department of Plant Biology, Uppsala BioCenter, Swedish University of Agricultural Sciences and Linnean Center for Plant Biology, Uppsala, Sweden.
² Department of Biology, University of Crete, Heraklion, Crete, Greece; Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology - Hellas, Heraklion, Crete, Greece.
³ Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium; VIB Center for Plant Systems Biology, 9052 Ghent, Belgium; Department of Biomolecular Medicine, Ghent University, 9000 Ghent, Belgium; VIB Center for Medical Biotechnology, 9000 Ghent, Belgium. Electronic address: simon.stael@psb.vib-ugent.be.
⁴ Department of Plant Biology, Uppsala BioCenter, Swedish University of Agricultural Sciences and Linnean Center for Plant Biology, Uppsala, Sweden; Department of Biology, University of Crete, Heraklion, Crete, Greece; Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology - Hellas, Heraklion, Crete, Greece.

PMID: 32191869
DOI: 10.1016/j.tplants.2020.01.002

Abstract

Hormonal pathways often converge on transcriptional repressors that can be degraded by the proteasome to initiate a response. We wish to draw attention to developments in a less-explored proteolytic branch called 'limited proteolysis' that, in addition to the classical proteolytic pathways, seems to regulate auxin and ethylene signaling.

Keywords: auxin; ethylene; phytohormone signaling; processing bodies; proteoforms; proteolysis.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Indoleacetic Acids*
Proteasome Endopeptidase Complex*
Proteolysis
Transcription Factors

Substances

Indoleacetic Acids
Transcription Factors
Proteasome Endopeptidase Complex