Acute promyelocytic leukemia presenting with atypical basophils

Afshin Shameli; Kareem Jamani

doi:10.1002/ccr3.2686

Acute promyelocytic leukemia presenting with atypical basophils

Clin Case Rep. 2020 Feb 5;8(3):584-585. doi: 10.1002/ccr3.2686. eCollection 2020 Mar.

Authors

Afshin Shameli¹, Kareem Jamani²

Affiliations

¹ Division of Hematology Alberta Precision Laboratories, and Department of Pathology and Laboratory Medicine University of Calgary Calgary AB Canada.
² Division of Hematology and Hematological Malignancies Department of Medicine University of Calgary Calgary AB Canada.

Abstract

We describe a case of acute promyelocytic leukemia with circulating aberrant basophils. Recent studies have shown that basophilic differentiation is not uncommon in APL and likely under-recognized in morphologic and immunophenotypic assessments.

Keywords: PML‐RARA; acute promyelocytic leukemia; basophils; flow cytometry.