A case of rectal ulcers during aspirin therapy in acute Kawasaki disease

Pediatr Rheumatol Online J. 2020 Mar 17;18(1):24. doi: 10.1186/s12969-020-0414-6.

Abstract

Kawasaki disease (KD) is an acute febrile multisystem vasculitis and has been recognized to be one of the most common causes of acquired heart disease in children. Although gastrointestinal symptoms including vomiting, diarrhea, and abdominal pain are not uncommon in KD patients, KD with lower gastrointestinal bleeding is quite rare. Here, we describe a 3-year-old boy with typical KD who had lower gastrointestinal bleeding caused by rectal ulcers on the third day of aspirin therapy.

Keywords: Aspirin; Gastrointestinal hemorrhage; Kawasaki disease; Rectal ulcer.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Aspirin / adverse effects*
  • Child, Preschool
  • Colitis / etiology
  • Colitis / pathology
  • Gastrointestinal Hemorrhage / etiology*
  • Gastrointestinal Hemorrhage / pathology
  • Humans
  • Male
  • Mucocutaneous Lymph Node Syndrome / complications
  • Mucocutaneous Lymph Node Syndrome / drug therapy*
  • Platelet Aggregation Inhibitors / adverse effects*
  • Proctitis / etiology
  • Proctitis / pathology
  • Rectal Diseases / etiology*
  • Rectal Diseases / pathology
  • Ulcer / etiology*
  • Ulcer / pathology

Substances

  • Platelet Aggregation Inhibitors
  • Aspirin