Second-hit APC mutation in a familial adamantinomatous craniopharyngioma

Neuro Oncol. 2020 Jun 9;22(6):889-891. doi: 10.1093/neuonc/noaa060.

Authors

Alexander Gorelyshev¹, Nadia Mazerkina¹, Olga Medvedeva², Evgeny Vasilyev¹, Vasily Petrov¹, Marina Ryzhova³, Sergey Gorelyshev², Anatoly Tiulpakov¹

Affiliations

¹ Department and Laboratory of Inherited Endocrine Disorders, Endocrinology Research Center, Moscow, Russian Federation.
² Department of Pediatric Neurosurgery, Burdenko National Medical Research Center for Neurosurgery, Moscow, Russian Federation.
³ Department of Neuropathology, Burdenko National Medical Research Center for Neurosurgery, Moscow, Russian Federation.

No abstract available

Keywords: APC; CTNNB1; brain tumors; craniopharyngioma; whole exome sequencing.

Publication types

Case Reports
Letter

MeSH terms

Adenomatous Polyposis Coli Protein / genetics*
Adult
Craniopharyngioma* / genetics
Female
Humans
Mutation
Pituitary Neoplasms* / genetics
Young Adult
beta Catenin / genetics

Substances

APC protein, human
Adenomatous Polyposis Coli Protein
beta Catenin