Mood disorders and outcomes in lung cancer patients undergoing surgery: a brief summery

Future Oncol. 2020 Jun;16(16s):41-44. doi: 10.2217/fon-2018-0835. Epub 2020 Mar 13.

Abstract

Cancer is a leading cause of death worldwide. Literature reports depression and anxiety are the most common psychiatric symptoms in cancer patients. Notably, lung cancer is associated with major depressive disorder in 5-13% of cases. The present article aims to give an overview regarding the impact of mood disorders on the outcomes of patients affected by lung cancer. Our review showed that pharmacological treatment and psychotherapy can be useful to improve the quality of life of patients with lung cancer. Moreover, the treatment of depression and anxiety can be associated with a reduced mortality. In conclusion, it is important to consider psychiatric care as important as other adjuvant oncologic therapies in patients with cancer.

Keywords: anxiety; depression; lung cancer; mood disorder; thoracic surgery.

Publication types

  • Review

MeSH terms

  • Anxiety / epidemiology
  • Anxiety / etiology
  • Anxiety / psychology
  • Anxiety / therapy*
  • Citalopram / therapeutic use
  • Cognitive Behavioral Therapy / methods
  • Combined Modality Therapy / methods
  • Depression / epidemiology
  • Depression / etiology
  • Depression / psychology
  • Depression / therapy*
  • Humans
  • Lung Neoplasms / mortality
  • Lung Neoplasms / psychology
  • Lung Neoplasms / surgery*
  • Patient Care Team
  • Pneumonectomy / adverse effects*
  • Pneumonectomy / psychology
  • Pneumonectomy / rehabilitation
  • Postoperative Complications / epidemiology
  • Postoperative Complications / etiology
  • Postoperative Complications / psychology
  • Postoperative Complications / therapy*
  • Quality of Life
  • Randomized Controlled Trials as Topic
  • Risk Factors
  • Selective Serotonin Reuptake Inhibitors / therapeutic use
  • Sertraline / therapeutic use
  • Suicide, Attempted / prevention & control
  • Suicide, Attempted / psychology
  • Survival Rate
  • Treatment Outcome

Substances

  • Serotonin Uptake Inhibitors
  • Citalopram
  • Sertraline