OBJECTIVE. The purpose of this article is to provide an up-to-date guide for radiologists on imaging and systemic therapies in myeloma and related conditions, with a focus on radiologic findings for diagnosis and treatment response assessment. CONCLUSION. Knowledge of the unique imaging presentations of myeloma is highly useful for radiologists. An understanding of the utility of different imaging modalities and the systemic therapies used in multiple myeloma is also critical in the realm of oncologic imaging.
Keywords: International Myeloma Working Group; multiple myeloma; oncologic imaging; oncologic staging; systemic therapies; whole-body low-dose CT.