Analysis of the Effect of Nine Consecutive Years' Intensive Management and Number of Times Achieving the Target Control on Endpoint Events in T2DM Patients in Sanlitun Community Health Service Center in Beijing

Chen-Mei Zhao; Xue-Li Cui; Gang Wan; Yu-Zhe Lu; Yu-Qin Niu; Cheng-Yu Su; Shuo Cao; Guan-Xiu Liang; Hong-Wei Chen; Jing Li; Xia Lu; Zhi-Yun Deng; Xue-Hui Yu; Wen-Xia Yang; Jian-Hua Li; Hua Fan; Mao-Xia Yang; Yan Fu; Su-Ping Wei; Zhi-Na He; Xue-Lian Zhang; Shen-Yuan Yuan

doi:10.1155/2020/3646342

Analysis of the Effect of Nine Consecutive Years' Intensive Management and Number of Times Achieving the Target Control on Endpoint Events in T2DM Patients in Sanlitun Community Health Service Center in Beijing

Int J Endocrinol. 2020 Feb 20:2020:3646342. doi: 10.1155/2020/3646342. eCollection 2020.

Authors

Chen-Mei Zhao¹, Xue-Li Cui¹, Gang Wan², Yu-Zhe Lu¹, Yu-Qin Niu¹, Cheng-Yu Su¹, Shuo Cao¹, Guan-Xiu Liang¹, Hong-Wei Chen¹, Jing Li¹, Xia Lu¹, Zhi-Yun Deng¹, Xue-Hui Yu¹, Wen-Xia Yang¹, Jian-Hua Li¹, Hua Fan¹, Mao-Xia Yang¹, Yan Fu¹, Su-Ping Wei¹, Zhi-Na He¹, Xue-Lian Zhang³, Shen-Yuan Yuan³

Affiliations

¹ Sanlitun Community Health Service Center, Beijing, China.
² Medical Records and Statistics Department, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
³ Department of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.

Abstract

Objective: To investigate the effect of intensive management and achieving the target control more than 3 times on endpoint events during 9 consecutive years' annual assessment in type 2 diabetes (T2DM) patients in the Sanlitun Community Health Service Center in Beijing, including blood glucose, blood pressure, lipids profiles, and the joint target control.

Methods: In Beijing Community Diabetes Study (BCDS), 224 patients with T2DM from the Sanlitun Community Health Service Center were enrolled in 2008. All patients were randomly assigned to the intensive management group (n = 113) and the standard management group (n = 113) and the standard management group (.

Results: During the nine-year follow-up, the abscission number was 35 (14.29%), among which 14 (12.39%) was in the intensive management group and 21 (18.92%) was in the standard management group. The incidence of diabetic retinopathy (6 cases, 5.41%) and diabetic nephropathy (13 cases, 11.71%) in the standard management group was significantly higher than that in the intensive management group (1 case, 0.88%; 5 cases, 4.42%), respectively (P < 0.05). However, there were no significant differences on the other endpoint events between the two groups (P < 0.05). However, there were no significant differences on the other endpoint events between the two groups (P < 0.05). However, there were no significant differences on the other endpoint events between the two groups (P < 0.05). However, there were no significant differences on the other endpoint events between the two groups (P < 0.05). However, there were no significant differences on the other endpoint events between the two groups (.

Conclusions: The intensive management can effectively reduce the occurrence of microvascular complications. The incidence of all-cause death and the other endpoint events decreased in T2DM patients who achieved the joint target control more than 3 times during the nine-year management, which improved survival time and life quality. This trial is registered with ChiCTR-TRC-13003978 and ChiCTR-OOC-15006090.