[Prevalence and risk factors of ischemic stroke in rural areas of Liaoning province]

Zhonghua Xin Xue Guan Bing Za Zhi. 2020 Feb 24;48(2):148-153. doi: 10.3760/cma.j.issn.0253-3758.2020.02.011.
[Article in Chinese]

Abstract

Objective: To explore the prevalence and risk factors of ischemic stroke in rural areas of Liaoning province. Methods: The study was a cross-sectional survey. From September 2017 to May 2018, a total of 10 926 rural residents aged ≥40 years were investigated in Chaoyang county, Lingyuan, Liaoyang county and Donggang city of Liaoning province. The investigation included questionnaire survey, physical examination and laboratory examination.Univariate and multivariate logistic regression models were used to analyze the risk factors of ischemic stroke. Results: The prevalence of ischemic stroke in the rural areas of Liaoning province was 5.51% (602/10 926), and the standardized prevalence rate was 4.04%. The standardized prevalence rate of male (5.05%) is higher than that of female (3.44%). The prevalence of ischemic stroke increased with age in both males (P<0.01) and females (P<0.01). Multivariate logistic regression analysis showed that age increase(compared with 40-49 years old group, 50-59 years old, OR=2.08, 95%CI 1.31-3.30, P=0.02; 60-69 years old, OR=3.90, 95%CI 2.51-6.05, P<0.01; 70-79 years old, OR=5.32, 95%CI 3.37-8.34, P<0.01; ≥80 years old, OR=3.64, 95%CI 2.00-6.62, P<0.01), male(OR=2.35, 95%CI 1.95-2.84, P<0.01),family history of stroke(OR=2.18, 95%CI 1.83-2.60, P<0.01),coronary heart disease (OR=2.01, 95%CI 1.52-2.66, P<0.01), hypertension (OR=2.82, 95%CI 2.21-3.60, P<0.01), diabetes mellitus (OR=1.36, 95%CI 1.11-1.67, P=0.03) and overweight/obese (OR=1.22, 95%CI 1.02-1.47, P=0.03) were the major risk factors of ischemic stroke. Conclusions: The prevalence of ischemic stroke in rural areas of Liaoning province is high. Age, male, family history of stroke, coronary heart disease, hypertension, diabetes mellitus, overweight/obesity are the risk factors of ischemic stroke in rural areas of Liaoning province.

目的: 探讨辽宁省农村地区人群缺血性卒中的患病率及其危险因素。 方法: 该研究为横断面调查。于2017年9月至2018年5月在辽宁省朝阳县、凌源市、辽阳县和东港市对≥40岁的10 926位农村常住居民进行问卷调查、体格检查和实验室检查。采用单因素和多因素logistic回归模型分析缺血性卒中的危险因素。 结果: 辽宁省农村地区人群缺血性卒中粗患病率为5.51%(602/10 926),标化患病率为4.04%,其中男性标化患病率为5.05%,高于女性人群的3.44%,且无论男性还是女性患病率均随年龄增长而升高(P均<0.01)。多因素logistic回归分析结果显示,增龄[以40~49岁人群的OR值为1,50~59岁人群OR=2.08,95%CI 1.31~3.30,P=0.02;60~69岁人群OR=3.90,95%CI 2.51~6.05,P<0.01;70~79岁人群OR=5.32,95%CI 3.37~8.34,P<0.01;≥80岁,OR=3.64,95%CI 2.00~6.62,P<0.01)、男性(OR=2.35,95%CI 1.95~2.84,P<0.01)、卒中家族史(OR=2.18,95%CI 1.83~2.60,P<0.01)、冠心病(OR=2.01,95%CI 1.52~2.66,P<0.01)、高血压(OR=2.82,95%CI 2.21~3.60,P<0.01)、糖尿病(OR=1.36,95%CI 1.11~1.67,P=0.03)和超重/肥胖(OR=1.22,95%CI 1.02~1.47,P=0.03)是缺血性卒中的危险因素。 结论: 辽宁省农村地区人群缺血性卒中患病率高,增龄、男性、卒中家族史、冠心病、高血压、糖尿病、超重/肥胖是缺血性卒中的危险因素。.

Keywords: Prevalence; Risk factors; Stroke.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Brain Ischemia* / epidemiology
  • China / epidemiology
  • Cross-Sectional Studies
  • Female
  • Humans
  • Hypertension
  • Male
  • Middle Aged
  • Prevalence
  • Risk Factors
  • Rural Population
  • Stroke* / epidemiology