A large deletion, spanning exons 1 to 25 of F8 gene, and a high-titer factor VIII inhibitor, in severe hemophilia A

Affiliations

• ¹ Department of the Clinical Biochemistry, Faculty of Medical Sciences, Kateb University, Kabul, Afghanistan.
• ² Afghanistan National Charity Organization for Special Diseases (ANCOSD), Kabul, Afghanistan.
• ³ Department of Clinical Biochemistry, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
• ⁴ Iranian Molecular Medicine Network, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran.
• ⁵ Iranian Comprehensive Hemophilia Care Center (ICHCC), Tehran, Iran.
• ⁶ Anesthesiology Department, Anesthesiology Research Center, Shahid Beheshti University of Medicine, Tehran, Iran.
• ⁷ Department of Public Health, Ghalib University, Kabul, Afghanistan.
• ⁸ Dr. Zeinali's Medical Genetics Laboratory, Kawsar human genetics research center, Tehran, Iran.
• ⁹ Department of Hematology and Blood Transfusion, School of Allied Medicine, Iran University of Medical Sciences, Tehran, Iran.