Yeast (Saccharomyces cerevisiae) GC/EI/MS metabolomics dataset

Data Brief. 2020 Jan 30:29:105208. doi: 10.1016/j.dib.2020.105208. eCollection 2020 Apr.

Abstract

Gas chromatography-electron impact-mass spectrometry (GC/EI/MS) global profiling of the endo-metabolome of wild and genetically engineered yeast (Saccharomyces cerevisiae) strains was performed. The strains were treated or not with sub-lethal doses of the fungicide flusilazole, in order to mine the involvement of the ABC transporter YCF1, which is located in the yeast vacuole membrane, in its resistance to fungicides. Raw GC/EI/MS total ion chromatograms (*.cdf format) of the yeast endo-metabolome were recoded, which are included in this article. Since yeast is a model organism, the dataset could serve as a reference for yeast metabolomics studies related to the investigation of the effects of bioactive ingredients on its metabolism. The dataset support the research article "Karamanou D. and Aliferis K.A, 2019. The yeast (Saccharomyces cerevisiae) YCF1 vacuole transporter: evidence on its implication into the yeast resistance to flusilazole as revealed by GC/EI/MS metabolomics. Pest. Biochem. Physiol. doi: https://doi.org/10.1016/j.pestbp.2019.09.013". 10.1016/j.pestbp.2019.09.013.

Keywords: Fungal resistance; Plant protection products; Transporters; Yeast metabolomics.