Intense 68Ga-Pentixafor Activity in Aldosterone-Producing Adrenal Adenomas

Jie Ding; Anli Tong; Yushi Zhang; Jin Wen; Li Huo

doi:10.1097/RLU.0000000000002946

Intense 68Ga-Pentixafor Activity in Aldosterone-Producing Adrenal Adenomas

Clin Nucl Med. 2020 Apr;45(4):336-339. doi: 10.1097/RLU.0000000000002946.

Authors

Jie Ding¹, Anli Tong², Yushi Zhang³, Jin Wen³, Li Huo¹

Affiliations

¹ From the Department of Nuclear Medicine and Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine.
² Department of Endocrinology and Key Laboratory of Endocrinology, Ministry of Health.
³ Department of Urological Surgery, Peking Union Medical College (PUMC) Hospital, Chinese Academy of Medical Science and PUMC, Beijing, China.

PMID: 32108693
DOI: 10.1097/RLU.0000000000002946

Abstract

Ga-pentixafor, a ligand of CXCR4 (CXC chemokine receptor type 4), has been reported as a potential PET tracer to evaluate a variety of pathological entities. We report intense Ga-pentixafor activity on PET/CT in 2 patients in the histopathologically confirmed adrenal adenomas, which were the cause of their Conn syndrome.

Publication types

Case Reports

MeSH terms

Adrenal Cortex Neoplasms / diagnostic imaging*
Adrenocortical Adenoma / diagnostic imaging*
Adult
Coordination Complexes
Female
Humans
Middle Aged
Peptides, Cyclic
Positron Emission Tomography Computed Tomography*
Radiopharmaceuticals

Substances

68Ga-pentixafor
Coordination Complexes
Peptides, Cyclic
Radiopharmaceuticals