Targeting mitochondrial dysfunction in MAIT cells limits IL-17 production in obesity

Cell Mol Immunol. 2020 Nov;17(11):1193-1195. doi: 10.1038/s41423-020-0375-1. Epub 2020 Feb 27.

Abstract

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Gene Expression Regulation
  • Humans
  • Interleukin-17 / biosynthesis*
  • Mitochondria / pathology*
  • Mucosal-Associated Invariant T Cells / pathology*
  • Obesity / genetics
  • Obesity / pathology*
  • Reactive Oxygen Species / metabolism

Substances

  • Interleukin-17
  • Reactive Oxygen Species