Decolonization of multi-drug resistant bacteria by fecal microbiota transplantation in five pediatric patients before allogeneic hematopoietic stem cell transplantation: gut microbiota profiling, infectious and clinical outcomes

Pietro Merli; Lorenza Putignani; Annalisa Ruggeri; Federica Del Chierico; Livia Gargiullo; Federica Galaverna; Stefania Gaspari; Daria Pagliara; Alessandra Russo; Stefania Pane; Luisa Strocchio; Mattia Algeri; Francesca Rea; Erminia Francesca Romeo; Paola Bernaschi; Andrea Onetti Muda; Bruno Dallapiccola; Franco Locatelli

doi:10.3324/haematol.2019.244210

Decolonization of multi-drug resistant bacteria by fecal microbiota transplantation in five pediatric patients before allogeneic hematopoietic stem cell transplantation: gut microbiota profiling, infectious and clinical outcomes

Haematologica. 2020 Nov 1;105(11):2686-2690. doi: 10.3324/haematol.2019.244210.

Authors

Pietro Merli¹, Lorenza Putignani², Annalisa Ruggeri¹, Federica Del Chierico³, Livia Gargiullo⁴, Federica Galaverna¹, Stefania Gaspari¹, Daria Pagliara¹, Alessandra Russo³, Stefania Pane⁵, Luisa Strocchio¹, Mattia Algeri¹, Francesca Rea⁶, Erminia Francesca Romeo⁶, Paola Bernaschi⁷, Andrea Onetti Muda⁸, Bruno Dallapiccola⁹, Franco Locatelli¹⁰

Affiliations

¹ Hematology/Oncology, Cellular and Gene Therapy, Bambino Gesù Children's Hospital, Rome, Italy.
² Unit of Parasitology and of Human Microbiome, Bambino Gesù Children's Hospital, Rome, Italy.
³ Unit of Human Microbiome, Bambino Gesù Children's Hospital, Rome, Italy.
⁴ Unit of Immunology and Infectious Diseases, Bambino Gesù Children's Hospital, Rome, Italy.
⁵ Unit of Parasitology, Bambino Gesù Children's Hospital, Rome, Italy.
⁶ Digestive Endoscopy and Surgery Unit, Bambino Gesù Children's Hospital, Rome, Italy.
⁷ Unit of Microbiology, Bambino Gesù Children's Hospital, Rome, Italy.
⁸ Department of Laboratories, Bambino Gesù Children's Hospital, Rome, Italy.
⁹ Scientific Directorate, Bambino Gesù Children's Hospital, Rome, Italy.
¹⁰ Dept. of Hematology/Oncology, Cellular and Gene Therapy,Bambino Gesù Children Hospital,Rome.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Bacteria
Child
Fecal Microbiota Transplantation
Gastrointestinal Microbiome*
Hematopoietic Stem Cell Transplantation*
Humans
Pharmaceutical Preparations*

Substances

Pharmaceutical Preparations

Grants and funding

Funding: this study was partially supported by the Italian Ministero della Salute (Bando Ricerca Finalizzata 2013, Giovani Ricercatori section, code GR-2013-02357136 to PM).