Individual gene analyses of microtubule-based motor proteins in Dictyosteliumdiscoideum have provided a rough draft of its machinery for cytoplasmic organization and division. This review collates their activities and looks forward to what is next. A comprehensive approach that considers the collective actions of motors, how they balance rates and directions, and how they integrate with the actin cytoskeleton will be necessary for a complete understanding of cellular dynamics.
Keywords: Dictyostelium; cell motility; dynein; kinesin; microtubules.