Endoscopic Treatment of Solitary Colonic Ganglioneuroma

Toshio Arai; Hiroki Yamada; Takeya Edagawa; Satoshi Yoshida; Shunji Maekura; Kenichiro Nakachi

doi:10.1159/000505510

Endoscopic Treatment of Solitary Colonic Ganglioneuroma

Case Rep Gastroenterol. 2020 Jan 20;14(1):34-38. doi: 10.1159/000505510. eCollection 2020 Jan-Apr.

Authors

Toshio Arai¹, Hiroki Yamada¹, Takeya Edagawa¹, Satoshi Yoshida¹, Shunji Maekura², Kenichiro Nakachi¹

Affiliations

¹ Department of Gastroenterology, Hashimoto Municipal Hospital, Hashimoto, Japan.
² Department of Pathology, Hashimoto Municipal Hospital, Hashimoto, Japan.

Abstract

Ganglioneuromas (GNs) in adults are uncommon clinical entities, especially in the colon. Patients with GNs without multiple endocrine neoplasia or neurofibromatosis-I are normally asymptomatic; however, GNs can present with abdominal pain, weight loss, bleeding, and anemia, depending on the size and location. Here, we present a case of solitary colonic GN treated with endoscopic mucosal resection. A 40-year-old Japanese outpatient with a positive fecal occult blood test visited our hospital. We performed diagnostic colonoscopy, which revealed a polyp of 15-mm diameter in the ascending colon. Electromagnetic resonance imaging was performed, and the histological examination revealed benign polypoid spindle-cell proliferation, ganglion cells, and thick nerve bundles, which was positive for S-100 protein immunoreactivity consistent with GN.

Keywords: Colonoscopy; Fecal occult blood test; Ganglioneuroma.

Publication types

Case Reports