Use of Epimacular Amniotic Membrane Graft in Cases of Recurrent Retinal Detachment Due to Failure of Myopic Macular Hole Closure

Ophthalmic Surg Lasers Imaging Retina. 2020 Feb 1;51(2):101-108. doi: 10.3928/23258160-20200129-06.

Abstract

Background and objective: To study the anatomical and functional outcomes of using epimacular amniotic membrane graft (AMG) to close myopic macular holes (MMHs) in patients with recurrent retinal detachment (RD).

Patients and methods: Fourteen patients with recurrent MMH-RD were enrolled in a single-arm, prospective study. Pars plana vitrectomy with peeling of any residual internal limiting membrane, preserved AMG was placed over the macular hole (MH) after air-fluid exchange, all patient left on 16% of C2F6.

Results: Fourteen patients (11 females and three males) with an average age of 58.7 years were included; follow-up was 6 months. Thirteen patients (93%) showed retinal reattachment and closure of the hole confirmed by optical coherent tomography. The mean logMAR of best-corrected visual acuity improved to 1.38 compared to 2.2 preoperatively (P < .002, paired t-test), with no serious intraoperative or postoperative complications.

Conclusion: Epimacular AMG for MMH-RD is a safe and effective treatment for closure of myopic MHs. [Ophthalmic Surg Lasers Imaging Retina. 2020;51:101-108.].

MeSH terms

  • Adult
  • Aged
  • Amnion / transplantation*
  • Basement Membrane / surgery
  • Endotamponade
  • Female
  • Fluorocarbons
  • Humans
  • Male
  • Middle Aged
  • Prone Position
  • Prospective Studies
  • Recurrence
  • Retinal Detachment / etiology
  • Retinal Detachment / physiopathology
  • Retinal Detachment / surgery*
  • Retinal Perforations / complications*
  • Retinal Perforations / physiopathology
  • Retinal Perforations / surgery
  • Tomography, Optical Coherence
  • Treatment Failure
  • Visual Acuity / physiology
  • Vitrectomy

Substances

  • Fluorocarbons
  • perfluoroethane