Longitudinal clonal architecture of acute myeloid leukemia with NPM1 driver insertion, early TET2 mutations and secondary e6a2 BCR-ABL1 rearrangement

Leuk Lymphoma. 2020 Jul;61(7):1709-1713. doi: 10.1080/10428194.2020.1728751. Epub 2020 Feb 20.

Authors

Maria Pilar Gallego Hernanz^{1

2}, Nathalie Sorel³, Sabrina Bouyer⁴, Deborah Desmier^{1

2}, Mélanie Chollet⁴, Natacha Maillard^{1

2}, Françoise Brizard⁴, Niels Moya^{1

2}, Jose Miguel Torregrosa Diaz^{1

2}, Xavier Leleu^{1

2}, Jean-Claude Chomel³

Affiliations

¹ CHU de Poitiers, Service d'Oncologie Hématologique et Thérapie Cellulaire, Poitiers, France.
² INSERM, CIC-P 1402, Poitiers, France.
³ CHU de Poitiers, Service de Cancérologie Biologique, Poitiers, France.
⁴ CHU de Poitiers, Service d'Hématologie Biologique, Poitiers, France.

PMID: 32077355
DOI: 10.1080/10428194.2020.1728751

No abstract available

Publication types

Case Reports
Letter

MeSH terms

DNA-Binding Proteins
Dioxygenases
Female
Fusion Proteins, bcr-abl / genetics
Humans
Leukemia, Myeloid, Acute* / diagnosis
Leukemia, Myeloid, Acute* / genetics
Middle Aged
Mutation
Nuclear Proteins
Nucleophosmin
Proto-Oncogene Proteins

Substances

DNA-Binding Proteins
NPM1 protein, human
Nuclear Proteins
Proto-Oncogene Proteins
Nucleophosmin
Dioxygenases
TET2 protein, human
Fusion Proteins, bcr-abl