Pull-through procedure in children with Hirschsprung disease: A nationwide analysis on postoperative outcomes

J Pediatr Surg. 2020 May;55(5):899-903. doi: 10.1016/j.jpedsurg.2020.01.038. Epub 2020 Jan 31.

Abstract

Purpose: No nationwide studies on hospital readmissions exist for children who have undergone pull-through operations for Hirschsprung disease. The study aim is to identify determinants of postoperative discharge outcomes and hospital readmissions in children with Hirschsprung disease.

Methods: The Nationwide Readmissions Database for 2010-2014 was queried for children (<18yo) with Hirschsprung disease and whom had undergone pull-through procedure, utilizing ICD-9 codes 751.3 and 48.40-69, respectively. Outcomes included complications and readmissions at 30-day and 1-year. Results were weighted for national estimates.

Results: The cohort consisted of 3635 patients, 75% male and 79% < 1 year of age. Readmission rates at 30 days and 1-year were 20% and 36%, respectively. Overall, the most common diagnoses for readmission were gastrointestinal disorders (46%) and infections (39%). All age groups had a ≥ 10% readmission rate for gastrointestinal disorders. Infants were more likely to be admitted for enterocolitis and infections (16% and 15%), while children (1-6 years old) were most commonly readmitted for electrolyte disturbances (12%). Total hospitalization cost was over $162 million with $24 million from readmissions.

Conclusion: Pull-through procedure for Hirschsprung disease is associated with high readmissions and associated economic burden. Age specific interventions to prevent unnecessary readmissions could improve outcomes and curtail healthcare spending.

Type of study: Retrospective Comparative Analysis.

Level of evidence: Level III.

Keywords: Enterocolitis; Gastrointestinal; Hirschsprung disease; Pull-through; Readmissions.

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Cohort Studies
  • Databases, Factual
  • Female
  • Gastrointestinal Diseases / epidemiology
  • Health Care Costs / statistics & numerical data
  • Hirschsprung Disease / surgery*
  • Hospital Costs
  • Hospitalization / economics
  • Humans
  • Infant
  • Infections / epidemiology
  • Male
  • Patient Discharge
  • Patient Readmission / economics
  • Patient Readmission / statistics & numerical data*
  • Postoperative Complications / epidemiology
  • Postoperative Period
  • Retrospective Studies
  • Risk Factors