Eye metastasis in lung adenocarcinoma mimicking anterior scleritis: A case report

World J Clin Cases. 2020 Jan 26;8(2):410-414. doi: 10.12998/wjcc.v8.i2.410.

Abstract

Background: The eye is a rare site for lung cancer metastasis. Indeed, ocular metastasis is one of the greatest challenges to quality of life in a cancer patient. Here we present a patient with lung adenocarcinoma and ocular metastasis.

Case summary: The patient was a 70-year-old man diagnosed with lung adenocarcinoma who developed eye metastasis mimicking anterior scleritis. Brain magnetic resonance imaging showed an abnormal signal in the right eye. Based on next generation sequencing of the surgical specimen, the patient was shown to have a KRAS point mutation (p.G12D).

Conclusion: Multidiscipline expertise collaboration is needed to make the early diagnosis and determine the prompt treatment in patients. We hope to increase the awareness of the possibility of lung cancer metastasizing to the eye.

Keywords: Case report; Eye; KRAS mutation; Metastases; Non-small cell lung cancer.

Publication types

  • Case Reports