The dispensing of psychotropic medicines to older people before and after they enter residential aged care

Med J Aust. 2020 Apr;212(7):309-313. doi: 10.5694/mja2.50501. Epub 2020 Feb 11.

Abstract

Objective: To examine the prevalence of psychotropic medicine dispensing before and after older people enter residential care.

Design: Retrospective national cohort study; analysis of Registry of Senior Australians (ROSA) data.

Setting, participants: All concession card-holding residents of government-subsidised residential aged care facilities in Australia who entered residential care for at least three months between 1 April 2008 and 30 June 2015.

Main outcome measures: Proportions of residents dispensed antipsychotic, benzodiazepine, or antidepressant medicines during the year preceding and the year after commencing residential care, by quarter.

Results: Of 322 120 included aged care residents, 68 483 received at least one antipsychotic (21.3%; 95% CI, 21.1-21.4%), 98 315 at least one benzodiazepine (30.5%; 95% CI, 30.4-30.7%), and 122 224 residents at least one antidepressant (37.9%; 95% CI, 37.8-38.1%) during their first three months of residential care; 31 326 of those dispensed antipsychotics (45.7%), 38 529 of those dispensed benzodiazepines (39.2%), and 25 259 residents dispensed antidepressants (19.8%) had not received them in the year preceding their entry into care. During the first three months of residential care, the prevalence of antipsychotic (prevalence ratio [PR], 3.37; 95% CI, 3.31-3.43) and antidepressant dispensing (PR, 1.05; 95% CI, 1.04-1.07) were each higher for residents with than for those without dementia; benzodiazepine dispensing was similar for both groups (PR, 1.01; 95% CI, 0.99-1.02).

Conclusions: Dispensing of psychotropic medicines to older Australians is high before they enter residential care but increases markedly soon after entry into care. Non-pharmacological behavioural management strategies are important for limiting the prescribing of psychotropic medicines for older people in the community or in residential care.

Keywords: Antidepressive agents; Antipsychotic agents; Dementia.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Antidepressive Agents / administration & dosage*
  • Australia / epidemiology
  • Benzodiazepines / administration & dosage*
  • Dementia / drug therapy
  • Drug Utilization / statistics & numerical data*
  • Female
  • Homes for the Aged / organization & administration
  • Homes for the Aged / statistics & numerical data*
  • Humans
  • Male
  • Mortality
  • Nursing Homes / statistics & numerical data*
  • Registries
  • Retrospective Studies

Substances

  • Antidepressive Agents
  • Benzodiazepines