Osteonecrosis of the talus of a child with acute lymphoblastic leukemia: A case report

Serkan Bayram; Koray Şahin; Gökhan Polat

doi:10.1016/j.foot.2019.10.004

Osteonecrosis of the talus of a child with acute lymphoblastic leukemia: A case report

Foot (Edinb). 2020 Mar:42:101649. doi: 10.1016/j.foot.2019.10.004. Epub 2019 Oct 24.

Authors

Serkan Bayram¹, Koray Şahin², Gökhan Polat²

Affiliations

¹ Istanbul University, Istanbul Medical Faculty, Orthopedics and Traumatology Department, Turkey. Electronic address: dr.serkanbayram89@gmail.com.
² Istanbul University, Istanbul Medical Faculty, Orthopedics and Traumatology Department, Turkey.

PMID: 32035403
DOI: 10.1016/j.foot.2019.10.004

Abstract

Osteonecrosis (ON) is a disabling complication of acute lymphoblastic leukemia (ALL) treatment in children and young adults. Isolated talus involvement is thought to be uncommon. A unique case of a 11-year-old female patient with ON in her left talus which developed six months after the completion of chemotherapy that she received for ALL is reported. A conservative treatment protocol was followed including activity modification, analgesia and prevention of weight-bearing. However, the disease significantly progressed during follow-up period. The present study makes an important contribution to the literature with unusual involvement pattern and location of ON after ALL treatment and with a long follow-up duration. LEVEL OF EVIDENCE: IV.

Keywords: Acute lymphoblastic leukemia; Ankle; Avascular necrosis; Talus.

Publication types

Case Reports

MeSH terms

Child
Conservative Treatment
Female
Humans
Magnetic Resonance Imaging
Osteonecrosis / diagnostic imaging*
Precursor Cell Lymphoblastic Leukemia-Lymphoma / complications*
Radiography
Sclerosis / diagnostic imaging
Talus / diagnostic imaging
Talus / pathology*